Cefepime

Overview

4.5 out of 5 (19 Reviews)

Credits

1.00

Post Assessment Questions

5

Start Date

1 Sep 2023

Last Review Date

28 Feb 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Cefepime, a potent cephalosporin belonging to the beta-lactam class of antibiotics, addresses a spectrum of bacterial infections caused by gram-negative and gram-positive organisms. Cefepime's efficacy is validated by FDA approval for conditions including pneumonia, complicated and uncomplicated urinary tract infections, skin and soft tissue infections, complicated intra-abdominal infections (in conjunction with metronidazole), and as an empiric treatment for neutropenic fever. The mechanism of action inherent to cefepime aligns with other beta-lactam antibiotics, disrupting bacterial cell wall synthesis. By covalently binding to key enzymes engaged in the final step of transpeptidation during peptidoglycan wall synthesis, cefepime induces structural defects in the cell wall, culminating in autolysis and the subsequent demise of the infectious organism. This module meticulously elucidates the indications, contraindications, adverse effects, dosing parameters, and monitoring considerations associated with cefepime. This educational resource empowers clinicians to leverage cefepime effectively in managing bacterial infections among hospitalized patients.


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the indications for cefepime therapy based on bacterial infection type, susceptibility patterns, and antibiogram data.

  • Screen patients for risk factors such as age, renal impairment, and previous adverse reactions to cefepime to determine appropriateness for therapy.

  • Apply pharmacokinetic and pharmacodynamic principles to optimize cefepime dosing and ensure therapeutic drug concentrations.

  • Implement care with other healthcare professionals to ensure appropriate monitoring, management, and follow-up of patients receiving cefepime.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Laura C. on 5/16/2021

Travis V. on 1/24/2022

Preeti S. on 3/22/2022

Brandy M. on 5/16/2022

Nicole G. on 9/15/2022

Christine G. on 9/20/2022

Kimber E. on 10/18/2022

Gerri S. on 11/6/2022

Dr.NIRMALA M. on 11/25/2022

none

shawna v. on 12/21/2022

Kelly D. on 1/9/2023

Julia B. on 3/15/2023

Shirley A. on 4/19/2023

Christine G. on 5/30/2023

Everett M. on 11/8/2023

Sarah G. on 11/22/2023

Mary M. on 12/20/2023

Shruthi P. on 1/27/2024

Keenan H. on 3/31/2024

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