Sodium Channel Blocker Toxicity

Overview

4.5 out of 5 (10 Reviews)

Credits

1.00

Post Assessment Questions

5

Start Date

1 Sep 2023

Last Review Date

2 Mar 2024

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Sodium channel blocker toxicity is a critical aspect of clinical care given the widespread use of medications such as Vaughn Williams Class 1 antiarrhythmics, local anesthetics, and neuropathic pain treatments like tricyclic antidepressants (TCAs), anticonvulsants, and cocaine. Notable examples encompass quinidine, procainamide, lidocaine, mexiletine, phenytoin, flecainide, propafenone, carbamazepine, and lamotrigine, each with distinct applications and potential toxicities. The enduring relevance of TCAs like imipramine and amitriptyline in the United States and the toxicity risks posed by insecticides through sodium channel blockade necessitates a comprehensive understanding of the etiology, clinical presentation, evaluation, and management of this type of toxicity.

This activity underscores sodium channel blocker toxicity, emphasizing the potential for catastrophic consequences, including fatality, whether arising from intentional misuse or accidental exposure. Clinicians participating in this activity gain valuable insights into the nuanced roles of the interprofessional team in evaluating, diagnosing, and effectively managing sodium channel blockade toxicity. 


Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the signs and symptoms of sodium channel blocker toxicity to facilitate prompt recognition and intervention.

  • Screen patients for risk factors associated with sodium channel blocker toxicity, including concurrent medication use and recent dosage changes.

  • Select the treatment and management plan for patients with sodium channel blocker toxicity.

  • Implement interprofessional team strategies for improving care coordination and communication when managing patients with sodium channel blocker toxicity.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

Jason H. on 10/31/2021

Anastasiya P. on 5/8/2022

John M. on 10/9/2022

JAMES M. on 2/2/2023

Lillian O. on 4/4/2023

Jamie K. on 5/17/2023

mariam g. on 5/20/2023

Mary Y. on 8/25/2023

William L. on 11/28/2023

valerie b. on 12/25/2023

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