TPA Therapy

Overview

4.7 out of 5 (27 Reviews)

Credits

1.00

Post Assessment Questions

5

Start Date

1 Sep 2023

Last Review Date

1 Sep 2023

Expiration Date

31 Aug 2026

Estimated Time To Finish

60 Minutes


 
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Activity Description

Alteplase (tPA) is a powerful thrombolytic agent used in the lysis of acute thromboembolism. FDA-approved indications for alteplase include pulmonary embolism, myocardial infarction with ST-segment elevation (STEMI), ischemic stroke when given within 3 hours of the start of symptoms, and re-establishment of patency in occluded intravenous (IV) catheters. There are also off-label indications. This activity outlines the indications, mechanism of action, methods of administration, important adverse effects, contraindications, toxicity, and monitoring, of tPA therapy with agents like alteplase, so providers can direct patient therapy where they are indicated as part of the interprofessional team.

Target Audience

This activity has been designed to meet the educational needs of physicians, physician associates, nurses, pharmacists, and nurse practitioners.

Learning Objectives

At the conclusion of this activity, the learner will be better able to:

  • Identify the indications for initiating therapy with a tPA agent such as alteplase.
  • Review the mechanism of action of tissue plasminogen activators such as alteplase.
  • Summarize the contraindications and adverse event profile of tPA medications such as alteplase.
  • Describe interprofessional team strategies for improving care coordination and communication to properly use tPA agents like alteplase to improve patient outcomes in the varied scenarios where it can be effective.

Disclosures

StatPearls, LLC requires everyone who influences the content of an educational activity to disclose relevant financial relationships with ineligible companies that have occurred within the past 24 months. Ineligible companies are organizations whose primary business is producing, marketing, selling, re-selling, or distributing healthcare products used by or on patients. All relevant conflict(s) of interest have been mitigated. Hover over contributor names for financial disclosures. Others involved in planning this educational activity have no relevant financial relationships to disclose.

Commercial Support: This activity has received NO commercial support.

Continuing Education Accreditation Information

In support of improving patient care, StatPearls, LLC is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

 

Nurses: StatPearls designates this activity for 1.00 ANCC contact hour(s). Nurses should only claim credit commensurate with the extent of their participation in the activity.

Please consult your professional licensing board for information on the applicability and acceptance of continuing education credit for this activity.

Method of Participation and Credit

  1. Register for the activity.    
  2. Review the target audience, learning objectives, and disclosure information.
  3. Study the educational content of the enduring material.
  4. Choose the best answer to each activity test question. To receive credit and a certificate, you must pass the test questions with a minimum score of 100%.
  5. Complete the post-activity assessment survey.

If you have concerns regarding the CE/CME system, please contact support@statpearls.com.

Disclaimer

This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Faculty may discuss investigational products or off-label uses of products regulated by the US Food and Drug Administration. Readers should verify all information before employing any therapies described in this educational activity.

The information provided for this activity is for continuing education purposes only and is not meant to substitute for the independent medical/clinical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. The information presented does not necessarily reflect the views of StatPearls or any commercial supporters of educational activities on statpearls.com. StatPearls expressly disclaims responsibility for any adverse consequences resulting directly or indirectly from information in the course, for undetected error, or through a participant's misunderstanding of the content.

Unapproved Uses of Drugs/Devices: In accordance with FDA requirements, the audience is advised that information presented in this continuing education activity may contain references to unlabeled or unapproved uses of drugs or devices. Please refer to the FDA-approved package insert for each drug/device for full prescribing/utilization information.

Cancellation Policy: Please see the cancellation policy. StatPearls, LLC reserves the right to cancel any course due to unforeseen circumstances.

 

 
 

Reviews

stacey h. on 3/27/2021

Venkat Raghav A. on 3/28/2021

Aslihan Y. on 11/23/2021

VERNA J. on 1/23/2022

Sunil J. on 7/23/2022

Lisa R. on 8/27/2022

Anita L. on 10/17/2022

Daphne C. on 10/27/2022

Kristie S. on 11/30/2022

Kevin H. on 12/1/2022

Anna W. on 1/25/2023

Cynthia D. on 3/1/2023

Charles H. on 3/7/2023

Michele S. on 3/11/2023

EDUARDO R. on 5/5/2023

Israel G. on 5/13/2023

VLADIMIR E. on 7/14/2023

Rosemarie B. on 8/17/2023

Humayun Z. on 10/25/2023

Ann T. on 11/19/2023

Scott S. on 11/20/2023

Art L. on 12/27/2023

Lindsay W. on 1/2/2024

Saiko A. on 1/17/2024

Jonathan A. on 1/28/2024

Tami O. on 2/6/2024

Kerry K. on 2/12/2024

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