Ilioinguinal neuralgia is a frequent cause of pain in the lower abdomen and the upper thigh. The ilioinguinal nerve is a mixed nerve that originates from the anterior rami of T12 and L1 nerve roots. It emerges near the lateral border of the psoas major muscle and goes inferior through the anterior abdominal wall, being sub-peritoneal and anterior to the quadratus lumborum muscle until it reaches the iliac crest. Then the ilioinguinal nerve goes through the transverse abdominis and the internal oblique muscles. It becomes superficial by passing through the superficial inguinal ring anterior to the spermatic cord. It gives motor innervation to the transverse abdominis and the internal oblique muscles. Also, it carries sensory information from the anterior surface of the scrotum and root of the penis in males or labia majora and mons pubis in females, and a small area of the upper anteromedial thigh. Because of its long course, entrapment or injury of the nerve after lower abdomen surgeries is common. Male or female patients can complain of pain, paresthesia and abnormal sensation in the area supplied by the nerve.
Diagnosis of the ilioinguinal neuralgia requires a careful history, physical examination, electrophysiologic studies, and ultrasound examination. Treatment of the ilioinguinal neuralgia includes conservative measures as oral analgesics, anticonvulsants, rehabilitation as electro-analgesic currents, and myofascial release. If conservative measures do not control symptoms, ultrasound-guided block, hydro-dissection, or radio-frequency ablation of the nerve can provide satisfactory relief of symptoms. Resistant cases may require neurectomy.
3- Stretch trauma:
B) Idiopathic - nerve entrapment at:
These nerve entrapments often result from abnormalities in the musculoaponeurotic connective tissue (tight fascial planes).
Ilioinguinal neuralgia is a common cause of chronic lower abdominal and anterior pelvic pain. The ilioinguinal neuralgia is not uncommon following the surgical repair of an inguinal hernia, and it is rarely because of stretch or entrapment neuropathy.
A) In cases of nerve trauma, partial or complete transection can occur, In the cases of a total cut of the nerve, Wallerian degeneration may follow.
B) In cases of nerve entrapment:
The net result is progressive ischemia of the nerve, potetially leading to the following:
Entrapment neuropathies are common disorders which lead to significant disability. Correct diagnosis is essential for proper management. History taking and physical examination are a cornerstone in the diagnosis of the ilioinguinal neuralgia. Patients of ilioinguinal neuralgia complain from pain (mostly postsurgical) in the lateral aspect of the iliac fossa, lower abdomen, and upper thigh, as well as abnormal sensation in the cutaneous distribution of the nerve (hyperesthesia or hypoesthesia). On examination, there is tenderness on palpation 1 inch medial and inferior to the anterior superior iliac spine and impaired sensation along the sensory distribution of the nerve. Complete neurologic examination is mandatory to exclude genitofemoral neuralgia, lumbosacral radiculopathy, and plexopathy.
1-Ultrasound examination: tracing of the nerve starting from the psoas major border is difficult because of the small size of the nerve and the depth of the nerve, especially in obese patients. It is easy to trace the nerve at the iliac crest down to the superficial inguinal ring and see the cause of the entrapment (for example; scar of surgery). An ultrasound-guided block can confirm a diagnosis of the ilioinguinal neuralgia.
2-Electrophysiologic studies: benefit of the electrophysiologic examination for diagnosis of the ilioinguinal nerve injury is questionable. Electrophysiologic studies are more directed to exclude lumbar radiculopathy and plexopathy.
3-Magnetic resonance imaging: performed on the lumbosacral spine to exclude lumbar radiculopathies.
There are multiple strategies to treat chronic groin pain. The pain of neuropraxia is typically temporary and disappears with time. Sometimes, the chronic groin pain persists and interferes with the activities of daily living.
1 - Lifestyle modification:
B) Ultrasound-guided nerve block:
Aim: interruption of the neuronal transmission leading to temporary pain relief.
Substances injected: local anesthetics (with or without steroids) or neurolytic agents.
Principal: injection of these chemicals prevent neuronal transmission through ilioinguinal nerve fibers either by blocking membrane ion channels or by denaturation of axon proteins.
1 - Patient position: supine
2 - Use a linear probe with frequency ranging from 5 to 10MHZ
3 - Place the probe transversely and start scanning from the anterior superior iliac spine
The nerve lies between transversus abdominis and internal oblique muscles lateral to the inferior epigastric artery and the iliohypogastric nerve. Operators introduce needle from lateral to medial using an in-plane approach to place the injectate accurately around the nerve.
Indications: persistent interactable pain after the failure of conservative measures.
Principal: Neurectomy involves identifying and dissecting the nerve, proximal to the area of trauma, or if possible, the entire length of the nerve.
The approach can be open or laparoscopic.
Differential diagnosis includes:
A thorough history, physical examination, electrophysiologic studies, ultrasound examination, magnetic resonance imaging, and individual nerve block can help differentiate the exact cause of the lower abdomen and groin pain.
Chronicity of the pain after injury or entrapment of the ilioinguinal nerve is not uncommon. But, the majority of patients respond well to nerve block or surgical neurectomy.
2- Complications of the central painkillers as gabapentin:
Ultrasound guidance lowers the incidence of above-mentioned complications.
4- Complications of the neurectomy:
Prevention of the ilioinguinal neuralgia is possible; surgeons should work to avoid injury of the nerves near the field of the surgery and use meshes which don't induce fibrotic reactions. Nurses and therapists should teach patients a healthy lifestyle to minimize pain and improve the activities of daily living. The diagnosis and treatment of ilioinguinal neuralgia need an interprofessional approach. Collaboration between physiatrists, neurologists, pain physicians, and surgeons should direct a proper approach to therapy to improve prognosis.
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