The diaphragm is the arched, flat muscular structure that divides the thorax from the abdominal cavity. Diaphragmatic injuries are relatively uncommon, representing less than 1% of traumatic injuries. They are typically considered a marker of severe trauma due to the high rate of associated injury. Certain injury patterns increase the risk of diaphragmatic injury, and penetrating trauma is a more common mechanism than blunt trauma. While large diaphragmatic injuries may be clinically obvious in the acute setting, diaphragmatic injuries are often occult, and a high index of suspicion must be maintained to prevent missing this important diagnosis. A missed diaphragmatic injury may result in delayed herniation and strangulation of abdominal organs into the thoracic cavity through the unrepaired defect in the diaphragm. A thorough understanding of the anatomy, associated injuries, and pitfalls in diagnostic testing will assist in diagnosing this surgical condition.
Injury to the diaphragm may be due to penetrating or blunt trauma. Penetrating trauma with direct injury to the diaphragm is more common and accounts for about two-thirds of cases. Stab wounds are the most frequent etiology, followed by gunshot wounds and impalements. Penetrating trauma usually results in smaller, unilateral injuries, which are more likely to be missed in the initial evaluation. The remaining one-third is due to blunt trauma with the vast majority (90%) caused by motor vehicle crashes. Falls and crush injuries account for the remainder. Blunt trauma causes larger ruptures; up to one-third of these ruptures may be bilateral.
Like most traumatic conditions, the diaphragmatic injury is more common in males. Patients with blunt injuries tend to be older with a median age of 44 years. In contrast, those with penetrating injuries have a median age of 31 years. Patients with blunt injury also have higher injury severity scores (33 versus 24). More than 50% of patients with diaphragmatic injury will have significant associated injuries. Mortality varies with the mechanism and is reported at 25% for all patients diagnosed with a diaphragmatic injury. Mortality is greatest in patients with blunt injury mechanisms in the acute setting due to associated injuries. The mortality from delayed presentation with herniation of abdominal contents into the thorax, from previous penetrating trauma, is around 20% and is substantially higher when bowel strangulation occurs. Since small injuries to the diaphragm are frequently missed, the exact incidence is unknown but is reported in the National Trauma Data Bank at about 0.5%. The rate of diaphragmatic injury appears to be increasing, perhaps related to better early trauma care, enhanced detection, and increased survival rates in patients with severe injuries.
Penetrating diaphragmatic injury
The diaphragm separates the negative pressure thorax from the positive pressure abdomen and spans from the lower sternum anteriorly to as low as L3 posteriorly. Depending on the phase of respiration, the location can be quite variable, and wounds that appear to be remote from its perceived location may violate the diaphragm. Any penetrating injury to the abdomen or chest from the T4 through T12 dermatome anteriorly and the L3 region posteriorly should be considered to have potentially caused diaphragmatic injury. Left-sided injuries are more common, possibly due to protective shielding by the liver but also perhaps due to the mechanism as most are related to stabbings and assailants are more likely to be right-handed thus inflicting injuries on the victim’s left. Penetrating injuries tend to be smaller, most measuring less than 2 cm. As a result, penetrating injuries are more likely to be occult and frequently result in delayed diagnosis. Penetrating injuries are most commonly associated with liver, hollow viscous, and splenic injuries.
Blunt diaphragmatic injury
Rupture of the diaphragm occurs when intra-abdominal pressure suddenly rises above the tensile strength of the diaphragmatic tissue. Blunt trauma produces larger, radial tears, often measuring 5 cm to 15 cm. Like penetrating injury, blunt diaphragmatic injuries occur most frequently on the left side which may be due to a congenital area of weakness in the diaphragm or because the liver attenuates some of the compressive force. When present, right-sided injuries to the diaphragm have a higher mortality rate due to more severe associated injuries. As compared to penetrating injuries, patients with blunt injury have a higher rate of injury to the aorta, lung, pelvis, and spleen.
Clinical presentation varies widely based on the mechanism of injury. Because the diaphragm is integral to normal respiration, patients with diaphragmatic injury may present in respiratory distress. Most often, blunt diaphragmatic injuries are discovered during the evaluation and management of the associated injuries. A physical exam should focus on the airway, breathing, and circulation, with inspection for signs of mediastinal shift or lung displacement. When herniation of abdominal contents occurs, bowel sounds may be auscultated in the chest. Any patient with penetrating trauma in the zone of concern (described above) should be assessed for diaphragmatic injury. Less than half of diaphragmatic injuries are diagnosed preoperatively, and a high index of suspicion based on mechanism is required.
While findings may be obvious if there are bowel contents or a coiled nasogastric tube in the chest, chest radiographs are non-diagnostic in up to 40% of cases. This is particularly true in intubated patients as positive pressure ventilation prevents herniation of abdominal contents into the chest. Subtle findings may include elevation of the diaphragm, atelectasis or pleural effusion. Right-sided injuries, unless resulting in large defects, may be particularly difficult to identify on chest radiograph as the liver buttresses the diaphragm.
Ultrasound is frequently utilized in the early evaluation of trauma patients to assess for fluid in the abdomen, pericardium, and chest. An experienced operator may be able to visualize an injury to the diaphragm, but a negative study does not exclude the diagnosis.
Computed tomography (CT)
In hemodynamically stable patients, CT scanning may be useful in detecting diaphragmatic injury. Newer generation multidetector machines may detect even subtle injuries with a sensitivity of around 66.7%. However, most patients with penetrating injury still do not receive a correct preoperative diagnosis.
Thoracoscopy or Laparoscopy
Thoracoscopy may be used to visualize the diaphragm when the diagnosis is considered, but laparotomy is not required to manage other injuries. Laparoscopy has a sensitivity of about 88% and a sensitivity of nearly 100% in evaluating for diaphragmatic injury.
In the emergency department, a meticulous trauma evaluation with the management of the airway, breathing, and circulation is most important. Placement on an oral or nasogastric tube may be helpful in making the diagnosis if the tube remains in the chest and in decompressing the stomach contents thus preventing further herniation. In some settings, a chest tube, inserted carefully to avoid causing additional injury, should be placed to address associated hemothorax or pneumothorax. Injuries to the diaphragm do not heal spontaneously, so operative repair is required in almost all patients. All left-sided injuries require repair, as do most right-sided injuries. In the rare patient with a small, right-sided tear that is a candidate for expectant management, it is important for the patient to understand the risk of delayed rupture. Surgical management is often via transabdominal approach, typically during the laparotomy performed for other injuries. In less severely injured patients, a less invasive laparoscopic or even thoracoscopic approach may be appropriate.
The diagnosis of a diaphragmatic rupture is not easy, especially when the tear is small. Hence, the condition is best managed by a multidisciplinary team that includes a radiologist, general surgeon, thoracic surgeon and a trauma surgeon. Once diagnosed, the only treatment for a diaphragmatic tear is surgery. The surgery may be approached via the abdomen or thorax. In most cases, if there are no other injuries, the outcomes are excellent. However, if the diagnosis is missed, it can present later with herniation of bowel contents in the chest. (Level V)
|||Gooseman MR,Rawashdeh M,Mattam K,Rao JN,Vaughan PR,Edwards JG, Unifying classification for transdiaphragmatic intercostal hernia and other costal margin injuries†. European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 2019 Feb 15; [PubMed PMID: 30770701]|
|||Prezman-Pietri M,Rabinel P,Périé G,Georges B,Brouchet L,Vardon Bounes F, Thoracic Damage Control: Let's Think About Intrathoracic Packing. The American journal of case reports. 2018 Dec 24; [PubMed PMID: 30581190]|
|||Moon J,Kang BH, Lateral approach of exploratory laparotomy through the open chest wall injury. Trauma case reports. 2018 Dec; [PubMed PMID: 30533484]|
|||Chaganti P,Chao JH, Bent Out of Shape: A Case of Abdominal Pain. Pediatric emergency care. 2018 Oct 19; [PubMed PMID: 30346365]|
|||Kassem MM,Wallen JM, Esophageal Perforation, Rupture, And Tears 2018 Jan; [PubMed PMID: 30335331]|
|||Corbellini C,Costa S,Canini T,Villa R,Contessini Avesani E, Diaphragmatic rupture: A single-institution experience and literature review. Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma [PubMed PMID: 29052830]|
|||Kumar A,Bagaria D,Ratan A,Gupta A, Missed diaphragmatic injury after blunt trauma presenting with colonic strangulation: a rare scenario. BMJ case reports. 2017 Aug 7; [PubMed PMID: 28790100]|
|||Testini M,Girardi A,Isernia RM,De Palma A,Catalano G,Pezzolla A,Gurrado A, Emergency surgery due to diaphragmatic hernia: case series and review. World journal of emergency surgery : WJES. 2017; [PubMed PMID: 28529538]|
|||Memon MA,Fitztgibbons RJ Jr, The role of minimal access surgery in the acute abdomen. The Surgical clinics of North America. 1997 Dec; [PubMed PMID: 9431343]|
|||Weaver AA,Schoell SL,Talton JW,Barnard RT,Stitzel JD,Zonfrillo MR, Functional outcomes of thoracic injuries in pediatric and adult occupants. Traffic injury prevention. 2018 Feb 28; [PubMed PMID: 29584488]|