[1]
Eckes L,Tsokos M,Herre S,Gapert R,Hartwig S, Toxicological identification of diphenhydramine (DPH) in suicide. Forensic science, medicine, and pathology. 2013 Jun; [PubMed PMID: 23065653]
[2]
Gardner DM,Kutcher S, Dimenhydrinate abuse among adolescents. Canadian journal of psychiatry. Revue canadienne de psychiatrie. 1993 Mar; [PubMed PMID: 8467436]
[3]
Rowe C,Verjee Z,Koren G, Adolescent dimenhydrinate abuse: resurgence of an old problem. The Journal of adolescent health : official publication of the Society for Adolescent Medicine. 1997 Jul; [PubMed PMID: 9215510]
[4]
Hedegaard H,Bastian BA,Trinidad JP,Spencer M,Warner M, Drugs Most Frequently Involved in Drug Overdose Deaths: United States, 2011-2016. National vital statistics reports : from the Centers for Disease Control and Prevention, National Center for Health Statistics, National Vital Statistics System. 2018 Dec; [PubMed PMID: 30707673]
[5]
Mowry JB,Spyker DA,Cantilena LR Jr,McMillan N,Ford M, 2013 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 31st Annual Report. Clinical toxicology (Philadelphia, Pa.). 2014 Dec; [PubMed PMID: 25559822]
[6]
Nishino T,Wakai S,Aoki H,Inokuchi S, Cardiac arrest caused by diphenhydramine overdose. Acute medicine [PubMed PMID: 30338086]
[7]
Taglialatela M,Timmerman H,Annunziato L, Cardiotoxic potential and CNS effects of first-generation antihistamines. Trends in pharmacological sciences. 2000 Feb; [PubMed PMID: 10664607]
[8]
Varma A,Ford L,Patel N,Vale JA, Elimination half-life of diphenhydramine in overdose. Clinical toxicology (Philadelphia, Pa.). 2017 Jul; [PubMed PMID: 28349707]
[9]
Simons KJ,Watson WT,Martin TJ,Chen XY,Simons FE, Diphenhydramine: pharmacokinetics and pharmacodynamics in elderly adults, young adults, and children. Journal of clinical pharmacology. 1990 Jul; [PubMed PMID: 2391399]
[10]
Blyden GT,Greenblatt DJ,Scavone JM,Shader RI, Pharmacokinetics of diphenhydramine and a demethylated metabolite following intravenous and oral administration. Journal of clinical pharmacology. 1986 Sep-Oct; [PubMed PMID: 3760245]
[11]
Akutsu T,Kobayashi K,Sakurada K,Ikegaya H,Furihata T,Chiba K, Identification of human cytochrome p450 isozymes involved in diphenhydramine N-demethylation. Drug metabolism and disposition: the biological fate of chemicals. 2007 Jan; [PubMed PMID: 17020955]
[12]
Radovanovic D,Meier PJ,Guirguis M,Lorent JP,Kupferschmidt H, Dose-dependent toxicity of diphenhydramine overdose. Human [PubMed PMID: 11204550]
[14]
Chyka PA,Seger D,Krenzelok EP,Vale JA, Position paper: Single-dose activated charcoal. Clinical toxicology (Philadelphia, Pa.). 2005; [PubMed PMID: 15822758]
[15]
Scharman EJ,Erdman AR,Wax PM,Chyka PA,Caravati EM,Nelson LS,Manoguerra AS,Christianson G,Olson KR,Woolf AD,Keyes DC,Booze LL,Troutman WG, Diphenhydramine and dimenhydrinate poisoning: an evidence-based consensus guideline for out-of-hospital management. Clinical toxicology (Philadelphia, Pa.). 2006; [PubMed PMID: 16749537]
[16]
Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. Journal of toxicology. Clinical toxicology. 1999; [PubMed PMID: 10584586]
[20]
Höjer J,Troutman WG,Hoppu K,Erdman A,Benson BE,Mégarbane B,Thanacoody R,Bedry R,Caravati EM, Position paper update: ipecac syrup for gastrointestinal decontamination. Clinical toxicology (Philadelphia, Pa.). 2013 Mar; [PubMed PMID: 23406298]
[21]
Benson BE,Hoppu K,Troutman WG,Bedry R,Erdman A,Höjer J,Mégarbane B,Thanacoody R,Caravati EM, Position paper update: gastric lavage for gastrointestinal decontamination. Clinical toxicology (Philadelphia, Pa.). 2013 Mar; [PubMed PMID: 23418938]
[23]
Jang DH,Manini AF,Trueger NS,Duque D,Nestor NB,Nelson LS,Hoffman RS, Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose. Clinical toxicology (Philadelphia, Pa.). 2010 Nov; [PubMed PMID: 21171853]
[24]
Kamijo Y,Soma K,Sato C,Kurihara K, Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support. Clinical toxicology (Philadelphia, Pa.). 2008 Nov; [PubMed PMID: 18608279]
[25]
Sharma AN,Hexdall AH,Chang EK,Nelson LS,Hoffman RS, Diphenhydramine-induced wide complex dysrhythmia responds to treatment with sodium bicarbonate. The American journal of emergency medicine. 2003 May; [PubMed PMID: 12811715]
[26]
Burns MJ,Linden CH,Graudins A,Brown RM,Fletcher KE, A comparison of physostigmine and benzodiazepines for the treatment of anticholinergic poisoning. Annals of emergency medicine. 2000 Apr; [PubMed PMID: 10736125]
[27]
Abdi A,Rose E,Levine M, Diphenhydramine overdose with intraventricular conduction delay treated with hypertonic sodium bicarbonate and i.v. lipid emulsion. The western journal of emergency medicine. 2014 Nov; [PubMed PMID: 25493135]
[28]
Yu JH,Chen DY,Chen HY,Lee KH, Intravenous lipid-emulsion therapy in a patient with cardiac arrest after overdose of diphenhydramine. Journal of the Formosan Medical Association = Taiwan yi zhi. 2016 Nov; [PubMed PMID: 27421174]