The thoracolumbar spine area at T10-L2 is the most common region of the spine affected by trauma due to the specific biomechanics of this segment. This area is commonly referred to as the thoracolumbar junction. It is highly susceptible to injury because it is a transition area from the rigid and less mobile thoracic spine due to the attached ribs bilaterally to a more flexible caudal lumbar spine.
Injury to this area can result in a permanent neurological deficit from compression and injury to the conus medullaris or the descending nerve roots and warrants immediate attention and assessment. The most common mechanisms for thoracolumbar traumatic injuries include motor vehicle accidents, falls from height, recreational injuries, and work-related injuries. Most of them are high-velocity and high-energy injuries, which usually involve additional injuries. Consensus guidelines have been proposed for the systematic management and implementation of treatment algorithms, especially in multisystemic injuries. The American College of Surgeons provides the advanced trauma life support (ATLS) protocol for trauma providers, and evidence has demonstrated a reduction in morbidity and mortality with this implementation.
Injury to the thoracolumbar spine can occur from motor vehicle accidents, falls from height, recreational accidents, and occupational injuries. Because the thoracolumbar junction is more vulnerable than other segments of the spine, it is a very common area of injury due to its intrinsic biomechanics.
In the event of high-velocity spine injuries, there is an associated 25% risk for accompanying spinal cord injury (SCI), which can subsequently have devastating effects on the patient with loss of individual productive years and an associated high cost to society. As many as 25% of thoracolumbar fractures have another spine fracture elsewhere, most commonly the cervical spine.
Thoracolumbar traumatic injury was most commonly reported in the 15-29 year age group before 2000, but now the median age is 35. Approximately 27% of the patients with thoracolumbar junction injuries had neurological deficits, which results in detrimental effects on society due to lifelong disability and loss of productive economic years. Approximately 70% of these fractures occur without immediate neurological injury, and eventually, 55% remain neurologically intact. Of the 45% who develop neurological symptoms, 26% develop an incomplete injury, and 19% develop a complete injury. Up to 75% of spine fractures occur in the T10-L2 area.
According to the United States National Spinal Cord Injury Statistical Center, in approximately 54 cases per million people, 17,000 new spinal cord injury cases occur each year. Over 250,000 patients are currently living with permanent deficits. Blunt trauma is associated with an incidence of 1.9% thoracic fractures.
The incidence of thoracolumbar junction fractures after motor vehicle accidents is approximately 2.4%, but it has been increasing over the years. In blunt trauma patients, thoracolumbar junction fractures had an incidence of 6.9%. A review of patients with blunt trauma who underwent a chest/abdomen/pelvis computed tomographic (CT) scan showed that up to 25% had thoracolumbar fractures. Several fractures were undetected in the plain X-ray films. In adults, motor vehicle accidents were the most common mechanism in 36.70% of the cases, followed by falls from height for 31.70%. For people with paraplegia, the average lifetime costs are approximately 2.5 million dollars per patient.
A report from China found a thoracolumbar junction fracture incidence rate of 2.4 patients per million with a mean age of 49 years, with a male to female ratio of 1.4:1.
In children, thoracolumbar fractures are rare, with a reported incidence as low as 2% of all spine fractures. However, other series have reported an incidence of 5%-34%. The most common mechanism is falling from a height, with 25% presenting a complete deficit, and approximately 20% requiring surgery.
Transitional zones of the spine have a characteristic higher degree of flexibility and degrees of motion; however, this can make these segments more prone to injury. The thoracolumbar region is a fulcrum between the more rigid thoracic segment with facets that are coronally oriented to prevent flexion-extension, translation, and rotation and the lumbar segment whose facets are oriented sagittally to allow flexion-extension movement. This anatomical setup makes the T10-L2 segment the most mobile and vulnerable portion of the spine. Also, at the transitional point for the thoracic spine (T11 and T12), the ribs do not articulate anteriorly with the sternum, distinguishing them as floating ribs. At the thoracolumbar junction, the stiff kyphotic thoracic spine meets the caudal lordotic lumbar spine.
The kinetic energy conveyed to this region can make it vulnerable to degenerative disease pathologies and traumatic injuries in higher energy mechanisms. Energy transferred from an impact at any anatomical level of the spine can accumulate and produce stress in the thoracolumbar junction. Many biochemical changes occur secondary to the impact, including ischemia, free radicals, vasoconstriction, intracellular influx of calcium ions, lipid peroxidation, and excitotoxins.
The majority of thoracolumbar junction fractures result from high impact trauma, including motor vehicle accidents and falls. A detailed patient history helps contextualize the type of mechanism involved in the injury. This will be most relevant in the neurologically stable patient. A low energy mechanism such as a ground-level fall is usually without associated neurological injury. Patients can present with associated neurological injury, which will show signs and symptoms during the neurological exam.
If the patient is critically ill and on mechanical ventilation, history will have to be obtained from family members, paramedics, other clinicians, and the patient's medical chart. Associated back pain with details such as location, quality, character, duration, and aggravating factors are standard attributes to be assessed and critical for associated injuries in other systems.
The patient who suffered a thoracolumbar junction fracture may present on a physical exam with intact function, incomplete deficits, or complete neurological deficits. The level of injury at the conus region can determine the deficit that the patient presents with. If the affected area is in the transition area, it can cause symptoms of both upper and lower motor neuron dysfunction.
If the lesion is above the conus, only upper motor signs and symptoms will be elicited; if the lesion is below, then lower motor signs and symptoms will be found. Patients usually have a mix of upper and lower motor neuron symptoms due to many exiting nerve roots from the conus medullaris in this region. Injuries that occur above T10 are more likely to result in complete neurological deficits, while injuries below L1 are more likely to result in radicular symptoms. This is due to the anatomic position of the spinal cord, where the conus medullaris usually do not extend below the level of L1.
There may be overt signs on the physical exam such as widened spaces between spinous processes or displacement of spinous processes from the midline, which can be seen in the patient's physical exam on palpation and inspection when the patient is rolled over in the primary trauma survey.
A complete motor and sensory examination is performed with the cooperative patient. Once this information has been obtained, the American Spinal Injury Association (ASIA) score can be assigned to the patient's neurological physical exam. It is critical to evaluate the bulbocavernosus reflex to determine if the patient is in spinal shock. If hyperactive, it probably represents a complete spinal cord injury. A rectal exam is done to assess tone.
Initial triage is performed using the primary ATLS survey, ensuring that the airway is secured, breathing and ventilation are adequate, and there is proper cardiovascular support. After this initial assessment, the secondary survey focused on the spine will consist of a motor and sensory examination to determine the SCI level. The rectal exam for evaluation of tone, voluntary contraction, and sensation should never be overlooked. If the patient is critically ill and on mechanical ventilation, with associated head injuries such as traumatic brain injury (TBI), the rectal tone may be the only objective finding of the neurological physical exam in patients with SCI. The international standards for neurological classification of spinal cord injury, commonly referred to as the ASIA exam, was developed as a universal classification tool for SCI based on a standardized sensory and motor assessment. It is a system used to define and describe the extent and severity of a patient's SCI and determine future rehabilitation and recovery needs. It is ideally completed within 72 hours after the initial injury. The patient's grade is based on how much sensation and movement are detected below the injury level.
In the setting of a traumatic event suffered by the patient, especially a high-energy mechanism, it is imperative that full spinal imaging is performed as soon as the primary survey is completed. This should be performed once the patient is stabilized from acute life-threatening injuries (shock, TBI). Delaying time to image acquisition in an SCI setting with a neurological deficit may be detrimental to the patient by potentially decreasing the maximal benefit of early surgery. Delayed diagnosis of a thoracolumbar fracture or injury can occur in up to 5% of patients. In the case of unstable thoracolumbar fractures, it can result in neurologic deficits and pain.
Therefore, it is important for clinicians, including emergency department clinicians, traumatologists, neurosurgeons, paramedics, and other associated healthcare professionals, to have a high degree of suspicion when evaluating the patient. Regardless of whether the patient has a spine fracture or injury, a high suspicion makes the use of spine immobilization and precautions mandatory, until a spine fracture is ruled out. There are no validated algorithms to direct decision-making in terms of which patients benefit from thoracolumbar imaging studies and which do not.
Imaging of the spine can include simple spine x-ray films, CT scans, or magnetic resonance imaging (MRI). Spine x-ray films usually do not provide the amount of detail to characterize the type of fracture and are not routinely used. In some situations, plain radiographs, if they are the only modality available, can detect fractures or evaluate bone instability. On the other hand, a CT scan and MRI provide a higher resolution of structures. They allow an understanding of the type of fracture, which will subsequently influence the proposed treatment options.
CT scan will give an adequate assessment of bony structures, including the vertebral bodies, pedicles, laminae, facets, and transverse and spinous processes. In contrast, MRI will provide a better assessment of the ligamentous and the neural structures, including the spinal cord, cauda equina, conus medullaris, and spinal nerve roots. Therefore, in the case of a patient presenting with neurological deficits, MRI will most likely be performed for a complete management algorithm. Neurosurgery or orthopedic spine surgery services should be consulted as soon as images are obtained for proper evaluation and recommendations. If there is a documented neurological deficit on the physical exam of the patient and initial CT scan images are negative for fractures or dislocations, it is essential to perform an MRI. The MRI can identify bone marrow edema associated with an occult fracture, soft tissue changes, annular disruption, disruption of the posterior ligamentous complex, hemorrhage, herniated disk material, and the status of the spinal cord.
Although plain simple radiographs are not routinely used in the initial diagnosis and management of thoracolumbar junction fractures, they remain useful in the operating room, serving to aid with a proper assessment of the sagittal alignment, fracture level localization, and graft-construct positioning. They also serve as an inexpensive alternative on long-term surveillance for the development of deformity or pseudoarthrosis with considerably less radiation exposure per study than the CT scan.
Different classification schemes have been proposed by committees of clinicians and spine surgeons, and unfortunately, many early classification systems relied primarily on imaging findings alone. More modern and recent classification algorithms have been developed. The paradigm has shifted to include aspects of the neurological physical examination, such as deficits. The Spine Trauma Study Group developed a comprehensive classification system with prognostic significance that helps guide treatment decisions for operative versus nonoperative management of thoracolumbar junction fractures, called the thoracolumbar injury classification and severity (TLICS) scale.
Criteria involved in the classification system include the integrity of the posterior ligamentous complex, the injury mechanism or morphology of the fracture, and the presence of neurological injury. The fracture's morphology serves as a surrogate for immediate stability, whereas disruption of the posterior ligamentous complex serves as a surrogate for long-term stability. The comprehensive TLICS system can be seen below, in which a score of less than 4 suggests conservative treatment, and a score of greater than 4 suggests surgical intervention. If a patient has a score of 4, the surgeon can recommend surgical versus conservative management, with both options being accepted.
Compression fractures are the most common injuries and are usually stable injuries with intact posterior elements. Burst fractures have the anterior column and the posterior column involved and typically have retropulsed bone into the canal. Flexion-distraction injuries usually are one or two-level hyperflexion injuries through the soft-tissue ligaments or the bony structures. These involve the anterior and posterior columns and the posterior ligaments, including the ligamentum flavum, and represent an unstable injury as the fracture typically extends through the ligament and the anterior and posterior columns. Fracture dislocations are unstable and should be stabilized at the earliest possible opportunity.
Spinal precautions should be implemented in all trauma patients until a spine fracture is ruled out. Limiting flexion, extension, rotation, and twisting of the spine can help avoid exacerbating an injury to the spinal cord. Precautions can be lifted once radiographic images and physical exams are reassuring for no spinal instability. Maintaining perfusion to the spinal cord with supportive care, including airway, breathing, and circulation management with a mean arterial pressure above 85 mmHg, is essential to enhance spinal cord perfusion. Based on the amount of instability or neurological involvement, the patient may require emergency surgery.
Injuries at the thoracolumbar junction, although very common, comprise a heterogeneous group of injuries that has led to an increased discrepancy over the ideal surgical or nonsurgical management. The TLICS scale can provide insight into the treatment of the patient’s spinal fracture. Many surgeons agree that the concept of spine stability is one of the most critical factors in deciding if the thoracolumbar junction fracture require surgical treatment or can be managed conservatively. Disruption of the posterior ligamentous complex integrity raises the likelihood of instability when identified by MRI. Even without neurologic injury, many of these fractures will require operative intervention for stabilization due to the degree of bony or ligamentous injury that may be present.
Different studies have addressed the management of thoracolumbar fractures, with some prospective randomized controlled trials comparing operative versus conservative management of thoracolumbar burst fractures, reporting no clinically significant advantage with surgery.
Conservative management techniques include thoracolumbar orthosis, plaster cast, Jewett brace, and a plastic body cast for approximately 12 weeks. The majority of the compression fractures are stable and are treated with simple observation or an orthosis.
For surgical intervention, approach alternatives include anterior, posterior, lateral, or combined approaches. The operative planning and stabilization of these fractures usually include a multifactorial decision-making process. The key factor for deciding an anterior versus a posterior approach is the location of the pathology to be addressed. Different techniques include posterior segmental instrumentation and fusion with or without posterior decompression, percutaneous pedicle screw instrumentation, lateral interbody fusion, and anterior column fusion. Spinal neuromonitoring is routinely used during the surgery. Postoperative bracing does not offer an advantage after surgical stabilization; however, it can be used for comfort.
Burst fractures are stable if the posterior osteoligamentous complex and facet capsules are intact. Stable burst fractures can be treated with an orthosis. If unstable, posterior pedicle screw fixation of the adjacent levels is performed. If an anterior surgery is performed, the fractured bone is removed, and the defect filled with a solid bone graft or a metallic or synthetic cage. This technique restores the anterior column. Flexion-distraction injuries damage the posterior osteoligamentous complex. They are treated with posterior instrumentation and fusion over several levels to restore the sagittal alignment. Fracture-dislocations are very unstable and are treated with early decompression and posterior multilevel instrumentation and fusion. Many surgeons perform minimally invasive procedures to reduce the morbidity of open surgery for thoracolumbar spine trauma.
After a recent history of trauma, with new evidence of neurological deficit or pain, a traumatic fracture is commonly encountered, but pre-existing disorders have to be excluded.
Thoracolumbar junction fractures can have devastating effects on a patient's general healthcare and society with loss of individual productive years and associated exorbitantly high costs. In a systematic review, there is no advantage of a technique for one conservative management over another.
Factors for the development of neurological deficits include the sagittal diameter of the spinal canal and the amount of anterior vertebral compression. The degree of neurological recovery depends on fracture type, location, ASIA score, and presence of comorbidities. Early intervention in patients with neurologic deficits allows for a better prognosis.
Patients with ASIA impairment score D or E can recover and return to a health status similar to the population norms. Those patients with more significant neurologic deficits are less likely to return to work.
Thoracolumbar junction fractures can cause significant morbidity to a patient. Patients should avoid activities where they can have easy falls. Many patients suffer falls while climbing trees; therefore, protection and safety is always a priority. Security ropes and wire cables should be used if working at heights or during recreational sports. Driving under the influence of toxic drugs and alcohol should be avoided.
Depending on the neurologic deficit, patients may be able to return to work, but some may persist with disabling pain. The use of a postoperative brace does not influence pain, return to work, or instrumentation failure. Patients need to follow physical therapy recommendations for a faster return to a productive life.
While the emergency department clinician and traumatologists are almost always involved in the care of patients with a thoracolumbar spine fracture, it is essential to consult with an interprofessional team of specialists that include neurosurgeons, orthopedic spine surgeons, physiatrist, and other associated healthcare professionals. It is critical to have a high degree of suspicion when evaluating the patient. The nurses are also a vital member of the interprofessional group. They will monitor the patient, educate the patient and family, and help with the mobilization and avoidance of pressure ulcers. Neuroradiologists will determine the amount of bone and ligamentous injury. Pharmacists are essential to administer pre and postoperative medications for pain control and wound infection prophylaxis.
When the patient is to be discharged home, consultation should be made with a social worker, community nurses, occupational therapy, and physical therapy. One major complication associated with high morbidity and mortality is deep vein thrombosis. If the patient has paraplegia, prophylactic anticoagulation should be administered. Physical therapists will help with early ambulation in those with incomplete deficits. The earlier signs and symptoms of a complication are identified, the better the prognosis and outcome after appropriate management. Interprofessional communication is essential to provide the patient with an integrated care pathway combined with an evidence-based approach to evaluation and management for a good outcome.
|||Denis F, The three column spine and its significance in the classification of acute thoracolumbar spinal injuries. Spine. 1983 Nov-Dec; [PubMed PMID: 6670016]|
|||Navarro S,Montmany S,Rebasa P,Colilles C,Pallisera A, Impact of ATLS training on preventable and potentially preventable deaths. World journal of surgery. 2014 Sep; [PubMed PMID: 24770906]|
|||Mohammad A,Branicki F,Abu-Zidan FM, Educational and clinical impact of Advanced Trauma Life Support (ATLS) courses: a systematic review. World journal of surgery. 2014 Feb; [PubMed PMID: 24136720]|
|||Chapman JR,Agel J,Jurkovich GJ,Bellabarba C, Thoracolumbar flexion-distraction injuries: associated morbidity and neurological outcomes. Spine. 2008 Mar 15; [PubMed PMID: 18344859]|
|||Wood KB,Li W,Lebl DR,Ploumis A, Management of thoracolumbar spine fractures. The spine journal : official journal of the North American Spine Society. 2014 Jan; [PubMed PMID: 24332321]|
|||Katsuura Y,Osborn JM,Cason GW, The epidemiology of thoracolumbar trauma: A meta-analysis. Journal of orthopaedics. 2016 Dec; [PubMed PMID: 27504058]|
|||Liu B,Zhu Y,Liu S,Chen W,Zhang F,Zhang Y, National incidence of traumatic spinal fractures in China: Data from China National Fracture Study. Medicine. 2018 Aug; [PubMed PMID: 30170470]|
|||Bizimungu R,Sergio Alvarez,Baumann BM,Raja AS,Mower WR,Langdorf MI,Medak AJ,Hendey GW,Nishijima D,Rodriguez RM, Thoracic Spine Fracture in the Panscan Era. Annals of emergency medicine. 2020 Aug; [PubMed PMID: 31983495]|
|||Doud AN,Weaver AA,Talton JW,Barnard RT,Meredith JW,Stitzel JD,Miller P,Miller AN, Has the incidence of thoracolumbar spine injuries increased in the United States from 1998 to 2011? Clinical orthopaedics and related research. 2015 Jan; [PubMed PMID: 25115589]|
|||Berry GE,Adams S,Harris MB,Boles CA,McKernan MG,Collinson F,Hoth JJ,Meredith JW,Chang MC,Miller PR, Are plain radiographs of the spine necessary during evaluation after blunt trauma? Accuracy of screening torso computed tomography in thoracic/lumbar spine fracture diagnosis. The Journal of trauma. 2005 Dec; [PubMed PMID: 16394914]|
|||Li B,Sun C,Zhao C,Yao X,Zhang Y,Duan H,Hao J,Guo X,Fan B,Ning G,Feng S, Epidemiological profile of thoracolumbar fracture (TLF) over a period of 10 years in Tianjin, China. The journal of spinal cord medicine. 2019 Mar; [PubMed PMID: 29595401]|
|||Babu RA,Arimappamagan A,Pruthi N,Bhat DI,Arvinda HR,Devi BI,Somanna S, Pediatric thoracolumbar spinal injuries: The etiology and clinical spectrum of an uncommon entity in childhood. Neurology India. 2017 May-Jun; [PubMed PMID: 28488618]|
|||Dogan S,Safavi-Abbasi S,Theodore N,Chang SW,Horn EM,Mariwalla NR,Rekate HL,Sonntag VK, Thoracolumbar and sacral spinal injuries in children and adolescents: a review of 89 cases. Journal of neurosurgery. 2007 Jun; [PubMed PMID: 17566397]|
|||Saul D,Dresing K, Epidemiology of vertebral fractures in pediatric and adolescent patients. Pediatric reports. 2018 Mar 22; [PubMed PMID: 29721244]|
|||Wood EG 3rd,Hanley EN Jr, Thoracolumbar fractures: an overview with emphasis on the burst injury. Orthopedics. 1992 Mar; [PubMed PMID: 1553326]|
|||Shores A, Spinal trauma. Pathophysiology and management of traumatic spinal injuries. The Veterinary clinics of North America. Small animal practice. 1992 Jul; [PubMed PMID: 1641921]|
|||Harrop JS,Hunt GE Jr,Vaccaro AR, Conus medullaris and cauda equina syndrome as a result of traumatic injuries: management principles. Neurosurgical focus. 2004 Jun 15; [PubMed PMID: 15202874]|
|||Baranowski P, Application of the International Standards for the Neurological and Functional Classification of Spinal Cord Injuries (the ASIA scale). Ortopedia, traumatologia, rehabilitacja. 2000 Mar 30; [PubMed PMID: 18033209]|
|||Graves DE,Frankiewicz RG,Donovan WH, Construct validity and dimensional structure of the ASIA motor scale. The journal of spinal cord medicine. 2006; [PubMed PMID: 16572564]|
|||The 2019 revision of the International Standards for Neurological Classification of Spinal Cord Injury (ISNCSCI)-What's new? Spinal cord. 2019 Oct; [PubMed PMID: 31530900]|
|||Savic G,Bergström EM,Frankel HL,Jamous MA,Jones PW, Inter-rater reliability of motor and sensory examinations performed according to American Spinal Injury Association standards. Spinal cord. 2007 Jun; [PubMed PMID: 17387316]|
|||Roberts TT,Leonard GR,Cepela DJ, Classifications In Brief: American Spinal Injury Association (ASIA) Impairment Scale. Clinical orthopaedics and related research. 2017 May; [PubMed PMID: 27815685]|
|||Reid DC,Henderson R,Saboe L,Miller JD, Etiology and clinical course of missed spine fractures. The Journal of trauma. 1987 Sep; [PubMed PMID: 3656481]|
|||VandenBerg J,Cullison K,Fowler SA,Parsons MS,McAndrew CM,Carpenter CR, Blunt Thoracolumbar-Spine Trauma Evaluation in the Emergency Department: A Meta-Analysis of Diagnostic Accuracy for History, Physical Examination, and Imaging. The Journal of emergency medicine. 2019 Feb; [PubMed PMID: 30598296]|
|||Duane TM,Dechert T,Brown H,Wolfe LG,Malhotra AK,Aboutanos MB,Ivatury RR, Is the lateral cervical spine plain film obsolete? The Journal of surgical research. 2008 Jun 15; [PubMed PMID: 18498879]|
|||Rihn JA,Anderson DT,Harris E,Lawrence J,Jonsson H,Wilsey J,Hurlbert RJ,Vaccaro AR, A review of the TLICS system: a novel, user-friendly thoracolumbar trauma classification system. Acta orthopaedica. 2008 Aug; [PubMed PMID: 18766477]|
|||Lee JY,Vaccaro AR,Lim MR,Oner FC,Hulbert RJ,Hedlund R,Fehlings MG,Arnold P,Harrop J,Bono CM,Anderson PA,Anderson DG,Harris MB,Brown AK,Stock GH,Baron EM, Thoracolumbar injury classification and severity score: a new paradigm for the treatment of thoracolumbar spine trauma. Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association. 2005 Nov; [PubMed PMID: 16307197]|
|||Koh YD,Kim DJ,Koh YW, Reliability and Validity of Thoracolumbar Injury Classification and Severity Score (TLICS). Asian spine journal. 2010 Dec; [PubMed PMID: 21165314]|
|||Vaccaro AR,Lim MR,Hurlbert RJ,Lehman RA Jr,Harrop J,Fisher DC,Dvorak M,Anderson DG,Zeiller SC,Lee JY,Fehlings MG,Oner FC, Surgical decision making for unstable thoracolumbar spine injuries: results of a consensus panel review by the Spine Trauma Study Group. Journal of spinal disorders [PubMed PMID: 16462211]|
|||Emery SE,Pathria MN,Wilber RG,Masaryk T,Bohlman HH, Magnetic resonance imaging of posttraumatic spinal ligament injury. Journal of spinal disorders. 1989 Dec; [PubMed PMID: 2520080]|
|||Kliewer MA,Gray L,Paver J,Richardson WD,Vogler JB,McElhaney JH,Myers BS, Acute spinal ligament disruption: MR imaging with anatomic correlation. Journal of magnetic resonance imaging : JMRI. 1993 Nov-Dec; [PubMed PMID: 8280974]|
|||Terk MR,Hume-Neal M,Fraipont M,Ahmadi J,Colletti PM, Injury of the posterior ligament complex in patients with acute spinal trauma: evaluation by MR imaging. AJR. American journal of roentgenology. 1997 Jun; [PubMed PMID: 9168711]|
|||Lee HM,Kim HS,Kim DJ,Suk KS,Park JO,Kim NH, Reliability of magnetic resonance imaging in detecting posterior ligament complex injury in thoracolumbar spinal fractures. Spine. 2000 Aug 15; [PubMed PMID: 10954639]|
|||Wood KB,Bohn D,Mehbod A, Anterior versus posterior treatment of stable thoracolumbar burst fractures without neurologic deficit: a prospective, randomized study. Journal of spinal disorders [PubMed PMID: 15699801]|
|||Spiegl UJ,Fischer K,Schmidt J,Schnoor J,Delank S,Josten C,Schulte T,Heyde CE, The Conservative Treatment of Traumatic Thoracolumbar Vertebral Fractures. Deutsches Arzteblatt international. 2018 Oct 19; [PubMed PMID: 30479250]|
|||Skoch J,Zoccali C,Zaninovich O,Martirosyan N,Walter CM,Maykowski P,Baaj AA, Bracing After Surgical Stabilization of Thoracolumbar Fractures: A Systematic Review of Evidence, Indications, and Practices. World neurosurgery. 2016 Sep; [PubMed PMID: 27262651]|
|||Avilés C,Flores S,Molina M, Conservative versus operative treatment for thoracolumbar burst fractures without neurologic deficit. Medwave. 2016 Mar 15; [PubMed PMID: 27028069]|
|||Aras EL,Bunger C,Hansen ES,Søgaard R, Cost-Effectiveness of Surgical Versus Conservative Treatment for Thoracolumbar Burst Fractures. Spine. 2016 Feb; [PubMed PMID: 26571155]|
|||Bakhsheshian J,Dahdaleh NS,Fakurnejad S,Scheer JK,Smith ZA, Evidence-based management of traumatic thoracolumbar burst fractures: a systematic review of nonoperative management. Neurosurgical focus. 2014; [PubMed PMID: 24981897]|
|||Tang P,Long A,Shi T,Zhang L,Zhang L, Analysis of the independent risk factors of neurologic deficit after thoracolumbar burst fracture. Journal of orthopaedic surgery and research. 2016 Oct 24; [PubMed PMID: 27788683]|
|||Muratore M,Allasia S,Viglierchio P,Abbate M,Aleotti S,Masse A,Bistolfi A, Surgical treatment of traumatic thoracolumbar fractures: a retrospective review of 101 cases. Musculoskeletal surgery. 2020 Feb 5; [PubMed PMID: 32026381]|
|||Schouten R,Keynan O,Lee RS,Street JT,Boyd MC,Paquette SJ,Kwon BK,Dvorak MF,Fisher CG, Health-related quality-of-life outcomes after thoracic (T1-T10) fractures. The spine journal : official journal of the North American Spine Society. 2014 Aug 1; [PubMed PMID: 24373680]|