Ramipril is an ACE-i (Angiotensin Converting Enzyme inhibitor) which is used medically for following different disease processes.
- Hypertension: The most common indication in current clinical practice.
- Prevention of Heart failure progression after myocardial infarction (MI): Ramipril is used after MI to prevent the progression of asymptomatic heart failure with reduced ejection fraction. Low dose ramipril often initiated within a few hours after the confirmed myocardial infarction.
- Risk Reduction: Ramipril is prescribed to reduce the risk of MI, stroke, and death in patients more than 55 years old with a high risk of atherosclerotic disease and major adverse cardiac events.
- Heart Failure with reduced ejection fraction (Off-label): It is used in the management of symptomatic heart failure with reduced ejection fraction to reduce morbidity and mortality.
There may be a few other unlicensed uses in other countries. Please refer to local guidelines for more details.